Twisted
To use prometheus with twisted, there is MetricsResource which exposes metrics as a twisted resource.
from prometheus_client.twisted import MetricsResource
from twisted.web.server import Site
from twisted.web.resource import Resource
from twisted.internet import reactor
root = Resource()
root.putChild(b'metrics', MetricsResource())
factory = Site(root)
reactor.listenTCP(8000, factory)
reactor.run()